THE PHOBR TWO-COMPONENT SYSTEM REGULATES ANTIBIOTIC BIOSYNTHESIS IN SERRATIA IN RESPONSE TO PHOSPHATE

Abstract Background Secondary metabolism in Serratia sp.ATCC 39006 (Serratia 39006) is controlled via a complex network of regulators, including a LuxIR-type (SmaIR) quorum sensing (QS) system.Here we investigate the molecular mechanism by which phosphate limitation controls biosynthesis of two antibiotic secondary metabolites, prodigiosin and carb

Abstract Conventional approaches to describe dark matter phenomenology at collider and (in)direct detection experiments in the form of dark matter effective field theory or simplified models suffer in general from drawbacks regarding validity at high energies and/or generality, limiting their applicability.In order to avoid these shortcomings, we p